Reggio, Patricia H: search on Z-Library

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1

Structure–activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists

John W. Huffman, Gulay Zengin, Ming-Jung Wu, Jianzhong Lu, George Hynd, Kristen Bushell, Alicia L.S. Thompson, Simon Bushell, Cindy Tartal, Dow P. Hurst, Patricia H. Reggio, Dana E. Selley, Michael P.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 546 KB

english, 2005

2

Stereoselective synthesis of the epimeric Δ7-tetrahydrocannabinols

John W. Huffman, W. Kenneth Banner, Grace K. Zoorob, H. Howard Joyner, Patricia H. Reggio, Billy R. Martin, David R. Compton

Journal:

Year:

1995

Language:

english

File:

PDF, 934 KB

english, 1995

3

An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol

Morales, Paula, Reggio, Patricia H., Jagerovic, Nadine

Journal:

Frontiers in Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.91 MB

english, 2017

4

An Update on Non-CB 1 , Non-CB 2 Cannabinoid Related G-Protein-Coupled Receptors

Morales, Paula, Reggio, Patricia H.

Journal:

Cannabis and Cannabinoid Research

Year:

2017

Language:

english

File:

PDF, 709 KB

english, 2017

5

Conformational Memories and the Endocannabinoid Binding Site at the Cannabinoid CB1 Receptor

Barnett-Norris, Judy, Hurst, Dow P., Lynch, Diane L., Guarnieri, Frank, Makriyannis, Alex, Reggio, Patricia H.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 506 KB

english, 2002

6

The Nucleotide-Free State of the Cannabinoid CB2/Gi Complex

Lynch, Diane L., Hurst, Dow P., Reggio, Patricia H.

Journal:

Year:

2020

Language:

english

File:

PDF, 453 KB

english, 2020

7

3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor

John W Huffman, Ross Mabon, Ming-Jung Wu, Jianzhong Lu, Richard Hart, Dow P Hurst, Patricia H Reggio, Jenny L Wiley, Billy R Martin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 333 KB

english, 2003

8

The therapeutic potential of orphan GPCRs, GPR35 and GPR55

Shore, Derek M., Reggio, Patricia H.

Journal:

Frontiers in Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.26 MB

english, 2015

9

Parameterization of Org27569: An allosteric modulator of the cannabinoid CB1 G protein-coupled receptor

Hadley A. Iliff, Diane L. Lynch, Evangelia Kotsikorou, Patricia H. Reggio

Journal:

Journal of Computational Chemistry

Year:

2011

Language:

english

File:

PDF, 959 KB

english, 2011

10

A molecular reactivity template for cannabinoid analgesic activity

Patricia H. Reggio, Vladimir Frecer, Aleksander P. Mazurek

Journal:

International Journal of Quantum Chemistry

Year:

1990

Language:

english

File:

PDF, 703 KB

english, 1990

11

The Cannabinoid Receptors Volume 5b || Models of Cannabinoid Inverse Agonism, Neutral Antagonism, and Agonism: Tools for Rational Drug Design

Reggio, Patricia H.

Year:

2009

Language:

english

File:

PDF, 915 KB

english, 2009

12

Secondary-Structure Analysis of Human Peripheral Cannabinoid Receptor CB2 Based on Solid-State 13C-,15N-MAS NMR and Molecular Dynamics Simulations

Kimura, Tomohiro, Vukoti, Krishna, Lynch, Diane L., Hurst, Dow P., Grossfield, Alan, Pitman, Michael C., Reggio, Patricia H., Yeliseev, Alexei A., Gawrisch, Klaus

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 36 KB

english, 2010

13

Activation of Inhibitory G Protein Catalyzed by GPCR: Molecular Dynamics Simulations of the Activated Cannabinoid CB2 Receptor/Gαi1β1γ2 Protein Complex

Singh, Jagjeet, Lynch, Diane, Grossfield, Alan, Leioatts, Nicholas, Pitman, Michael, Reggio, Patricia

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 44 KB

english, 2014

14

Pharmacophores for Ligand Recognition and Activation / Inactivation of the Cannabinoid Receptors

Reggio, Patricia

Journal:

Current Pharmaceutical Design

Year:

2003

Language:

english

File:

PDF, 393 KB

english, 2003

15

Phospholipid and Temperature Dependence of TRPV1 Dynamics

Lynch, Diane L., Muller, Chante, Hurst, Dow P., Reggio, Patricia H.

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 74 KB

2020

16

Therapeutic Exploitation of GPR18: Beyond the Cannabinoids?

Morales, Paula, Lago-Fernandez, Ana, Hurst, Dow P., Sotudeh, Noori, Brailoiu, Eugen, Reggio, Patricia H., Abood, Mary E, Jagerovic, Nadine

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 1.01 MB

2020

17

One for the Price of Two…Are Bivalent Ligands Targeting Cannabinoid Receptor Dimers Capable of Simultaneously Binding to both Receptors?

Glass, Michelle, Govindpani, Karan, Furkert, Daniel P., Hurst, Dow P., Reggio, Patricia H., Flanagan, Jack U.

Journal:

Trends in Pharmacological Sciences

Year:

2016

Language:

english

File:

PDF, 2.75 MB

english, 2016

18

Construction of a GPR3 Homology Model Using Conformational Memories

Morales, Paula, Hurst, Dow P., Reggio, Patricia H.

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 60 KB

english, 2017

19

GPCRs Moonlighting as Scramblases: Mechanism Revealed

Reggio, Patricia H.

Journal:

Year:

2018

Language:

english

File:

PDF, 576 KB

english, 2018

20

ChemInform Abstract: EIGENSCHAFTEN VON ATOMEN IN MOLEKUELEN 4. MITT. ATOMLADUNGEN IN EINIGEN LINEAREN MEHRATOMIGEN MOLEKUELEN

POLITZER, PETER, REGGIO, PATRICIA H.

Journal:

Chemischer Informationsdienst

Year:

1973

File:

PDF, 93 KB

1973

21

Analogs of JHU75528, a PET ligand for imaging of cerebral cannabinoid receptors (CB1): Development of ligands with optimized lipophilicity and binding affinity

Hong Fan, Evangelia Kotsikorou, Alexander F. Hoffman, Hayden T. Ravert, Daniel Holt, Dow P. Hurst, Carl R. Lupica, Patricia H. Reggio, Robert F. Dannals, Andrew G. Horti

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 887 KB

english, 2009

22

A search for properties which produce discrimination between cannabinoid psychoactivity and analgesic activity

Patricia H. Reggio

Journal:

International Journal of Quantum Chemistry

Year:

1992

Language:

english

File:

PDF, 828 KB

english, 1992

23

Inhibition of striatal dopamine release by CB1 receptor activation requires nonsynaptic communication involving GABA, H2O2, and KATP channels

Zsuzsanna Sidló, Patricia H. Reggio, Margaret E. Rice

Journal:

Neurochemistry International

Year:

2008

Language:

english

File:

PDF, 460 KB

english, 2008

24

Molecular Determinants for a Mutant Mu-Opioid Receptor in which Naloxone Acts as a Partial Agonist

Pearsall, Elizabeth, Law, Ping-Yee, Reggio, Patricia H.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 117 KB

english, 2012

25

Identification of an Endogenous Allosteric Modulator's Binding Site at the Human Cannabinoid-1 Receptor, Using Forced-Biased Metropolis Monte Carlo Simulated Annealing Method (MMC) and Molecular Dynamics

Shore, Derek M., Hurst, Dow P., Lynch, Diane L., Reggio, Patricia H.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 43 KB

english, 2015

26

Towards a better understanding of the cannabinoid-related orphan receptors GPR3, GPR6, and GPR12

Morales, Paula, Isawi, Israa, Reggio, Patricia H.

Journal:

Drug Metabolism Reviews

Year:

2018

Language:

english

File:

PDF, 1.92 MB

english, 2018

27

The Cannabinoid Receptors Volume 5b || Cannabinoid Agonist and Inverse Agonist Regulation of G Protein Coupling

Reggio, Patricia H.

Year:

2009

Language:

english

File:

PDF, 671 KB

english, 2009

28

Identification of Crucial Amino Acid Residues Involved in Agonist Signaling at the GPR55 Receptor

Lingerfelt, Mary A., Zhao, Pingwei, Sharir, Haleli P., Hurst, Dow P., Reggio, Patricia H., Abood, Mary E.

Journal:

Year:

2017

Language:

english

File:

PDF, 3.28 MB

english, 2017

29

Cannabinoid CB1 receptor recognition of endocannabinoids via the lipid bilayer: molecular dynamics simulations of CB1 transmembrane helix 6 and anandamide in a phospholipid bilayer

Diane L. Lynch, Patricia H. Reggio

Journal:

Journal of Computer-Aided Molecular Design

Year:

2006

Language:

english

File:

PDF, 514 KB

english, 2006

30

The Cannabinoid Receptors Volume 194 || Molecular Biology of Cannabinoid Receptors: Mutational Analyses of the CB Receptors

Reggio, Patricia H.

Year:

2009

Language:

english

File:

PDF, 691 KB

english, 2009

31

Endogenous lipid activated G protein-coupled receptors: Emerging structural features from crystallography and molecular dynamics simulations

Hurst, Dow P., Schmeisser, Marianne, Reggio, Patricia H.

Journal:

Chemistry and Physics of Lipids

Year:

2013

Language:

english

File:

PDF, 2.12 MB

english, 2013

32

Evidence against Cannabinoid Receptor Involvement in Intraocular Pressure Effects of Cannabinoids in Rabbits

Hodges, Linda C., Reggio, Patricia H., Green, Keith

Journal:

Ophthalmic Research

Year:

1997

Language:

english

File:

PDF, 623 KB

english, 1997

33

CBD: A New Hope?

Morales, Paula, Reggio, Patricia H.

Journal:

ACS Medicinal Chemistry Letters

Year:

2019

Language:

english

File:

PDF, 486 KB

english, 2019

34

The Cannabinoid Receptors Volume 1 || New Insights into the Endocannabinoid System by Using Cannabinoid Receptor Knockout Mice

Reggio, Patricia H.

Year:

2009

Language:

english

File:

PDF, 497 KB

english, 2009

35

A Novel Pain Management Paradigm: Conformational Studies of the Mu-Opioid Receptor

Poole, Elizabeth, Iliff, Hadley, Edwards, Brady, Hurst, Dow, Reggio, Patricia

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 39 KB

english, 2009

36

Chromenopyrazole, a Versatile Cannabinoid Scaffold with in Vivo Activity in a Model of Multiple Sclerosis.

Morales, Paula, Gómez-Cañas, Maria, Navarro, Gemma, Hurst, Dow P., Carrillo-Salinas, Francisco J., Lagartera, Laura, Pazos, Ruth, Goya, Pilar, Reggio, Patricia H., Guaza, Carmen, Franco, Rafael, Ferná

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.78 MB

english, 2016

37

Agonist alkyl tail interaction with cannabinoid CB1 receptor V6.43/I6.46 groove induces a helix 6 active conformation

Judy Barnett-Norris, Dow P. Hurst, Kurt Buehner, Juan A. Ballesteros, Frank Guarnieri, Patricia H. Reggio

Journal:

International Journal of Quantum Chemistry

Year:

2002

Language:

english

File:

PDF, 680 KB

english, 2002

38

Adamantyl Cannabinoids: A Novel Class of Cannabinergic Ligands

Lu, Dai, Meng, Zhaoxing, Thakur, Ganesh A., Fan, Pusheng, Steed, John, Tartal, Cindy L., Hurst, Dow P., Reggio, Patricia H., Deschamps, Jeffrey R., Parrish, Damon A.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 490 KB

english, 2005

39

International Cannabis Research Society Meeting Summary, Keystone, CO (June 19–20, 1992)

Martin, Billy R., Cabral, Guy, Childers, Steven R., Deadwyler, Sam, Mechoulam, Raphael, Reggio, Patricia

Journal:

Drug and Alcohol Dependence

Year:

1993

Language:

english

File:

PDF, 964 KB

english, 1993

40

Synthesis and pharmacology of 1-methoxy analogs of CP-47,497

John W. Huffman, Seon A. Hepburn, Patricia H. Reggio, Dow P. Hurst, Jenny L. Wiley, Billy R. Martin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 592 KB

english, 2010

41

Molecular Dynamics Simulations of the Endocannabinoid N -Arachidonoylethanolamine (Anandamide) in a Phospholipid Bilayer: Probing Structure and Dynamics

Lynch, Diane L., Reggio, Patricia H.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 458 KB

english, 2005

42

Properties of atoms in molecules. IV. Atomic charges in some linear polyatomic molecules

Politzer, Peter, Reggio, Patricia H.

Journal:

Journal of the American Chemical Society

Year:

1972

Language:

english

File:

PDF, 517 KB

english, 1972

43

A specific Role for Cholesterol at the Mu Opioid Homodimer Interface

Lynch, Diane L., Poole, Elizabeth B., Hurst, Dow P., Law, Ping Y., Pitman, Michael C., Reggio, Patricia H.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 37 KB

english, 2011

44

The Unusual Phenotype of the Mu Opioid Receptor S4.54A Mutant:An Exploration of Structural Origins using Conformational Memories

Pearsall, Elizabeth A., Law, Ping-Yee, Reggio, Patricia H.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 37 KB

english, 2013

45

ChemInform Abstract: Ligand—Ligand and Ligand—Receptor Approaches to Modeling the Cannabinoid CB1 and CB2 Receptors: Achievements and Challenges

Patricia H. Reggio

Journal:

Year:

1999

File:

PDF, 27 KB

1999

46

Global fold of human cannabinoid type 2 receptor probed by solid-state 13 C-, 15 N-MAS NMR and molecular dynamics simulations

Kimura, Tomohiro, Vukoti, Krishna, Lynch, Diane L., Hurst, Dow P., Grossfield, Alan, Pitman, Michael C., Reggio, Patricia H., Yeliseev, Alexei A., Gawrisch, Klaus

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2014

Language:

english

File:

PDF, 961 KB

english, 2014

47

Endocannabinoid Binding to the Cannabinoid Receptors: What Is Known and What Remains Unknown

Reggio, Patricia

Journal:

Current Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 829 KB

english, 2010

48

Opioid receptors: toward separation of analgesic from undesirable effects

Law, Ping-Yee, Reggio, Patricia H., Loh, Horace H.

Journal:

Trends in Biochemical Sciences

Year:

2013

Language:

english

File:

PDF, 1019 KB

english, 2013

49

Rational Design of Neutral Allosteric Modulators of the CB1 Receptor with Improved Receptor Interactions and Unique Pharmacology

Shore, Derek M., Hurst, Dow P., Navas, Frank J., Seltzman, Herbert H., Baillie, Gemma L., Ross, Ruth A., Reggio, Patricia H.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 55 KB

english, 2013

50

GPR35: Study of Class a GPCR Sequence Divergences using Conformational Memories

Lane, Thomas, Abood, Mary E., Reggio, Patricia H.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 43 KB

english, 2010

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